Activating homeostatic pathways for the treatment of metabolic disease
Advancing cancer treatment with scalable Targeted Alpha Therapy
Developing selective mTORC1 small-molecule therapies for TSC epilepsy
Developing small-molecule and biologic therapies for kidney diseases
Modular vaccine platform based on immuno-material technology
Harnessing alternative splicing to restore health
First-in-class nanotherapeutics for neurodegenerative diseases
Developing small-molecule therapies for cardiometabolic diseases
Topical therapeutics addressing the root cause of disease
Working to end the transplant shortage with Human Compatible xenotransplants
Developing transformational medicines for intractable diseases
Developing one-time in vivo treatments to precisely engineer cells
Modulating the immune system with bacterial peptides
Discovering novel immunology through skin
Developing novel antifungal treatments for invasive fungal infections
Human-first discovery of microbiome therapeutics
Elegantly designed, selectively delivered and activated mRNA 2.0
Repairing neural circuits with transplanted, stem cell-derived neurons
Mining nature to discover new carbohydrates
Developing a new drug class of stapled peptides for oncology
Developing targeted therapies for protein misfolding diseases
Developing tissue-selective RNAi therapies for autoimmune and cardiometabolic diseases
Transforming immunology therapies using machine learning
Harnessing the microbiome to treat and prevent inflammatory diseases
Developing next-generation antibody-drug conjugates
Developing treatments for substance use disorders
Developing targeted antibody therapies for cancer
Developing innovative neurodegenerative treatments
Eradicating chronic disease-causing bacteria with customized phage therapies
Engineering macrophages and monocytes to attack cancer
Decoding the role of biomolecular condensates in driving disease
Cell-free production of RNA at metric-ton scale
Using 3-D cell culture to predict the best drug for every cancer patient
Restoring patient microbiomes to improve cancer survival
Searching the natural world for gene editing systems
Developing advanced therapies for obesity and metabolic diseases
Using microbial nucleic acid to diagnose early-stage cancer
Getting gut bacteria back in balance through personalized diet and probiotics
Allogeneic, engineered cell therapies with broad applicability to multiple large indications
Industrializing drug discovery
Genome engineering technology leveraging mammal-derived enzymes and non-viral delivery
Developing antibodies that harness the body’s own regenerative pathways
Curative gene therapies, regenerative, and precision medicines for rare heart diseases
Rationally designed microbial consortia to tune the body’s ecosystem
Genetically engineering healthy cells to enable selective cancer targeting
